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Chinazolinone, 2. Mitt.: Synthese und einige Reaktionen von 2-Azidomethyl-3-aryl-4-chinazolinonen

Quinazolinones, 2. syntheses and some reactions of 2-azido-methyl-3-aryl-4-quinazolinones

  • Organische Chemie und biochemie
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Abstract

Starting with the chloromethyl compounds7 the new 2-azidomethyl-3-aryl-4-quinazolinones8 a-h were prepared, some of which have been reduced so far to the corresponding amines9 a, b, e, g by H2S in good yield. As a first example for the capability of the azides8 to undergo 1,3-dipolar cycloaddition the 2-quinazolinmethyl-1,2,3-triazol-4,5-dicarboxylicacid dimethylesters11 b, e, g were prepared by reacting8 with dimethylacetylenedicarboxylate (10).

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Authors and Affiliations

  1. Institut für Organische und Pharmazeutische Chemie, Universität Innsbruck, A-6020, Innsbruck, Österreich

    Rainer Domanig

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  1. Rainer Domanig
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1. Mitt.:Domanig R., Arch. Pharm., im Druck.

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Domanig, R. Chinazolinone, 2. Mitt.: Synthese und einige Reaktionen von 2-Azidomethyl-3-aryl-4-chinazolinonen. Monatshefte für Chemie 112, 1195–1202 (1981). https://doi.org/10.1007/BF00905474

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  • DOI: https://doi.org/10.1007/BF00905474

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