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The occurrence of three allelic markers in one particle of phage T4

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Summary

The analysis of the progeny from three-allelic, triparental one-factor crosses in T4 showed a fraction of phages carrying allthree markers inone particle. Thesethree-allelic heterozygotes were observed in therII-region as well as in the host range gene. Their frequency (0.01–0.04% of total yield) was in the range expected from theory. This result is discussed with respect to the current picture of circular permutation in phage T4.

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Literature

  • Benzer, S., andS. P. Champe: AmbivalentrII-mutants of phage T4. Proc. nat. Acad. Sci. (Wash.)47, 1025–1038 (1961).

    Google Scholar 

  • Bode, W.: Zur Natur der ausgedehnten Mutationen des Coliphagen T4. Z. Vererb.-Lehre94, 190–199 (1963).

    Google Scholar 

  • Bode, W., C. Bresch andR. Hertel: (Manuscript in preparation.) (1963).

  • Bresch, C.: Replication and recombination in bacteriophage. Z. Vererb.-Lehre93, 476–490 (1962).

    Google Scholar 

  • Chase, M., andA. D. Doermann: High negative interference over short segments of genetic structure of bacteriophage T4. Genetics43, 332–353 (1958).

    Google Scholar 

  • Doermann, A. D., andL. Boehner: An experimental analysis of bacteriophage heterozygotes. I. Mottled plaques from crosses involving sixrII loci. Virology (in press) (1963).

  • Hershey, A. D., andM. Chase: Genetic recombination and heterozygosis in bacteriophage. Cold Spr. Harb. Symp. quant. Biol.16, 471–479 (1951).

    Google Scholar 

  • Nomura, M., andS. Benzer: The nature of the “deletion” mutants in therII region of phage T4. J. molec. Biol.3, 684–692 (1961).

    Google Scholar 

  • Sechaud, J., G. Streisinger, H. Lanford, H. Reinhold andM. M. Stahl: The gross structure of the genome of phage T4. II. Proc. nat. Acad. Sci. (Wash.) (in press) (1963).

  • Streisinger, G.: The genetic control of host range and serological specificity bacteriophages T2 and T4. Virology2, 377–387 (1956).

    Google Scholar 

  • Streisinger, G. Pers. communication 1961 (quoted fromBresch 1962).

  • Streisinger, G., R. S. Edgar andG. H. Denhardt: The gross structure of the genome of phage T4. I. The circularity of the linkage map. Proc. nat. Acad. Sci. (Wash.) (in press) (1963 a).

  • Streisinger, G., M. M. Stahl andJ. Emrich: The gross structure of the genome of phage T4. III. The frequency of terminal-redundancy-heterozygotes in genomes containing deletions. Proc. nat. Acad. Sci. (Wash.) (in press) (1963 b).

  • Thomas jr., C. A.: The organisation of DNA in bacteriophage and bacteria. In: Molecular Genetics I, ed.J. H. Taylor, pp. 113–151. New York: Academic Press 1963.

    Google Scholar 

  • Womack, F. C.: Studies on the structure and replication of the heterozygote in bacteriophage T4. Ph. D. Thesis Vanderbilt University 1962.

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  1. Institut für Genetik der Universität zu Köln, Weyertal 115, 5000, Köln-Lindenthal

    R. Hertel

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  1. R. Hertel
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Hertel, R. The occurrence of three allelic markers in one particle of phage T4. Zeitschrift für Vererbungslehre 94, 436–441 (1963). https://doi.org/10.1007/BF00897599

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  • DOI: https://doi.org/10.1007/BF00897599

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