Summary
Mitotic activity and glycogen content in the liver of white rats was measured one h after feeding at 10 a.m. or 10 p.m. after a 24-h fast. Irrespective of the time at which the rat was fed the maximal mitotic activity was found to occur between 6 and 8 a.m., and the minimal rate during the greater part of the 24 h. When the animals were fed in the morning the glycogen content rose gradually, reaching a maximum at a period when mitotic activity was minimal. With an evening feed the highest glycogen content occurred at 6 a.m., at the period of maximum mitotic rate. Subsequently both the number of mitoses and the glycogen content decreased.
Thus there was no direct relationship between glycogen formation and mitotic activity.
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Sokolova, L.V. Daily periodicity of mitotic division and the glycogen content of the white rat liver. Bull Exp Biol Med 58, 849–852 (1964). https://doi.org/10.1007/BF00862699
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DOI: https://doi.org/10.1007/BF00862699