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Transformed steroids

Communication 43. Synthesis of pentacyclic analogs of progesterone with an additional ring in the 16, 17 positions

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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    The thermal and catalytic diene condensation of 16-dehydropregnenolone acetate with acyclic dienes leads to the formation of the corresponding pentacyclic adducts.

  2. 2.

    Of the formed adducts, the pentacyclic analogs of progesterone with an additional six-membered E ring in the 16, 17 positions were synthesized, some of which exhibited noticeable gestagenic activity.

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Authors and Affiliations

  1. N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, USSR

    A. A. Akhrem, L. E. Kulikova, I. S. Levina & Yu. A. Titov

Authors
  1. A. A. Akhrem
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  2. L. E. Kulikova
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  3. I. S. Levina
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  4. Yu. A. Titov
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Additional information

Deceased.

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1358–1363, June, 1972.

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Akhrem, A.A., Kulikova, L.E., Levina, I.S. et al. Transformed steroids. Russ Chem Bull 21, 1308–1312 (1972). https://doi.org/10.1007/BF00854550

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  • DOI: https://doi.org/10.1007/BF00854550

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