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Microbiological transformations of steroids

3. Reduction of 17α,21-deoxy steroids with the aid of actinomyces albus 3006

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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Summary

A culture of Actinomyces albus 3006 is incapable of reducing the 20-keto group of 17α,21-deoxy-Δ4-3-keto steroids except when the substrate contains an oxygen function in the 11-position.

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Author information

Authors and Affiliations

  1. Institute for the Chemistry of Natural Products and Institute of Microbiology, Academy of Sciences of the USSR, USSR

    Leonid M. Kogan, I. V. Ulezlo, I. K. Kozlova, N. N. Suvorov, S. L. Portnova, G. K. Skryabin & I. V. Torgov

Authors
  1. Leonid M. Kogan
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  2. I. V. Ulezlo
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  3. I. K. Kozlova
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  4. N. N. Suvorov
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  5. S. L. Portnova
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  6. G. K. Skryabin
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  7. I. V. Torgov
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Additional information

We are deeply grateful to Dr. M. Shirasaka (Japan), Dr. P. Djassi (USA), and Dr. B. Camerino (Italy) for kindly providing samples of 7β-hydroxyprogesterone, 15α-hydroxyprogesterone, and 15β-hydroxyprogesterone.

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya No. 11, pp. 2008–2015, November, 1964

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Kogan, L.M., Ulezlo, I.V., Kozlova, I.K. et al. Microbiological transformations of steroids. Russ Chem Bull 13, 1908–1913 (1964). https://doi.org/10.1007/BF00844486

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  • DOI: https://doi.org/10.1007/BF00844486

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