Abstract
Motoneurons of the lumbosacral region of the spinal cord were studied during local botulinus paralysis. The development of paralysis of the poisoned limb was accompanied by lowering of the membrane potential, the amplitude of the antidromic action potentials and of mono- and polysynaptic EPSPs, and the input resistance, and by an increase in the critical depolarization level of the soma membrane of phasic motoneurons in the affected segments of the spinal cord. The excitability of the tonic motoneurons was substantially unchanged in the course of development of local botulism.
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Mikhailov, V.V., Mikhailov, V.V. Effects of pathogenic action of botulinus toxin of spinal motoneurons of various types. Bull Exp Biol Med 80, 1288–1290 (1975). https://doi.org/10.1007/BF00835164
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DOI: https://doi.org/10.1007/BF00835164