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The effect of adrenocorticotropic hormone on post-mortem rigidity

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Mice which are normally resistant to staphylococci will usually become infected if a preliminary injection of cortisone is given. In addition to producing some reduction of the phagocytic activity of the macrophages of the lungs, cortisone delays the leucocytic response occurring within the first few hours after the infection. The effect is more pronounced with large doses of bacteria. American cortisone is more effective in this respect than the French preparation. Prolonged use of cortisone has no effect on the development of staphylococcal infection. Infection of the lungs by fungi occurs commonly in animals so treated.

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Authors and Affiliations

  1. Department of Pharmacology, Leningrad Pediatric Medical Institute, Leningrad, USSR

    I. V. Markova

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  1. I. V. Markova
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Markova, I.V. The effect of adrenocorticotropic hormone on post-mortem rigidity. Bull Exp Biol Med 51, 680–684 (1961). https://doi.org/10.1007/BF00833890

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  • DOI: https://doi.org/10.1007/BF00833890

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