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Effect of carbidine on content and deposition of adrenergic neurotransmitter in synaptic vesicles

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of the original Soviet psychotropic agent carbidine on the content and deposition of adrenergic mediator in the synaptic vesicles of sympathetic nerve fibers of the rat vas deferens was studied by electron-microscopic cytochemistry. The results showed that carbidine can reduce the reserves of monoamines deposited in synaptic vesicles but does not affect the uptake and accumulation of exogenous noradrenalin by synaptic vesicles.

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Arefolov, V.A., Panasyuk, L.V. Effect of carbidine on content and deposition of adrenergic neurotransmitter in synaptic vesicles. Bull Exp Biol Med 80, 1208–1212 (1975). https://doi.org/10.1007/BF00833163

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  • DOI: https://doi.org/10.1007/BF00833163

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