Abstract
Addition of ethanolamine, phosphoethanolamine, or phosphatidylethanolamine in concentrations of 0.5 μM to the brain mitochondrial fraction increases endogenous respiration and the P/O ratio. In insulin hypoglycemia, addition of these substances leads to a proportional increase in the level of respiration and inorganic phosphorus, so that the supply of energy remains at the characteristic level for intact rats.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
A. Lehninger, Mitochondria: Molecular Basis of Structure and Function, Benjamin (1964).
V. P. Skulachev, Transformation of Energy in Biomembranes [in Russian], Moscow (1972).
E. G. Ball and C. D. Joel, Internat. Rev. Cytol.,13, 99 (1962).
C. H. Fleisher and G. Brierley, Biochem. Biophys. Res. Commun.,5, 367 (1961).
D. Green and C. H. Fleisher, Biochim. Biophys. Acta,70, 554 (1969).
R. D. Hill, S. Ford, K. H. Byington, et al., Arch. Biochem.,127, 756 (1968).
O. H. Lowry and J. A. Lopez, J. Biol. Chem.,162, 421 (1964). As in Russian original.-Editor.
O. H. Lowry, N. J., Rosebrough, A. L. Farr, et al., J. Biol. Chem.,193, 265 (1951).
M. G. MacFarlane, Biochem. J.,47, 29 (1960).
P. Mandel, T. Borkowski, and S. Harth, J. Neurochem.,8, 126 (1961).
R. S. May, A. B. Kamle, and J. P. Acosta, J. Membrane Biol.,98, 207 (1970).
J. Nachbaur and P. M. Vogwais, Biochim. Res. Commun.,33, 315 (1968).
G. R. Rossi, Z., Sartorelli, et al., Biochim. Biophys Acta,98, 207 (1970).
M. Waite, Biochemistry,8, 2536 (1969).
Rights and permissions
About this article
Cite this article
Karagezyan, K.G., Ovsepyan, L.M. Role of ethanolamine, phosphoethanolamine, and phosphatidylethanolamine in oxidative phosphorylation of albino rat brain mitochondria. Bull Exp Biol Med 80, 1195–1196 (1975). https://doi.org/10.1007/BF00833158
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00833158