Abstract
Experiments on isolated rabbit hearts with complete atrioventricular block showed that Luciani periods arise under the influence of acetylcholine (1·10−7–2·10−6 g/ml) or eserine (1·10−7–2·10−6 g/ml). These periods disappear as a result of the action of atropine (1·10−6 g/ml). Microelectrode recordings showed that Luciani periods produced under the influence of acetylcholine or eserine are due to periodic inhibition of pacemaker activity of the Purkinje fibers. This supperssion of pacemaker activity is regarded as the result of relative insufficiency of the process of active ion transport.
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Literature Cited
E. B. Babskii and A. V. Gritsak, Fiziol. Zh. SSSR,59, 1516 (1973).
E. B. Babskii and A. V. Gritsak, in: Biophysics of Membranes [in Russian], Kaunas (1973), p. 58.
E. B. Babskii and S. K. Saidkarimov, Vestn. Akad. Med. Nauk SSSR, No. 11, 29 (1970).
E. B. Babskii, L. S. Ul'yaninskii, and S. K. Saidkarimov, in: Current Problems in Physiology [in Russian], Kishinev (1969), p. 41.
E. B. Babskii and L. S. Ul'yaninskii, Vestn. Akad. Med. Nauk SSSR, No. 2, 23 (1968).
N. N. Demin and E. N. Makarova, Dokl. Akad. Nauk SSSR,175, 730 (1967).
Z. P. Kometiani and A. A. Kalandarishvili, Biofizika,14, No. 2, 312 (1969).
H. Lu, G. Lange, and C. M. Brooks, Circulat. Res.,17, 460 (1965).
G. Obrecht-Coutris, E. Coraboeuf, and G. Douarin, C. R. Acad. Sci. (Paris),267, 1102 (1968).
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Gritsak, A.V., Ul'yaninskii, L.S. Luciani periods arising by the action of acetylcholine and eserine on automatic activity of Purkinje fibers. Bull Exp Biol Med 79, 382–385 (1975). https://doi.org/10.1007/BF00832702
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DOI: https://doi.org/10.1007/BF00832702