Abstract
The cyclic AMP concentration was measured by a radioimmunoassay method in slices of rat parotid gland after incubation for 12–14 h. In each concrete experiment only one gland was used. Pieces for measurement of cyclic AMP concentration were taken at 10-min intervals for 2 h. Rhythmic changes in the cyclic AMP concentration with a period of 20–50 min were found. The period of the cyclic AMP rhythm is similar to the period of fluctuations in other parameters discovered previously on the same object: the dry weight of the cells, rate of protein synthesis, and ornithine decarboxylase activity.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
V. Ya. Brodskii, J. Theor. Biol.,55, 167 (1975).
G. I. Dorofeev, L. A. Kozhemyakin, and V. T. Ivashkin, Cyclic Nucleotides and Adaptation of the Organism [in Russian], Leningrad (1978).
E. A. Luriya and I. E. P'yanchenko, Byull. Éksp. Biol. Med., No. 6, 80 (1967).
N. V. Nechaeva, T. B. Aizenshtadt, and E. A. Luriya, Tsitologiya, No. 4, 465 (1970).
N. V. Nechaeva, “Biological rhythms in the secretory function of a salivary gland (quantitative cytochemical investigation)”, Author's Abstract of Doctoral Dissertation, Moscow (1977).
K. N. Yarygin, N. V. Nechaeva, V. I. Fateeva, et al., Byull. Éksp. Biol. Med., No. 12, 730 (1978).
A. L. Steiner, Pharmacol. Rev.,25, 309 (1973).
J. Yasumasu, A. Fujiwara, and K. Ishida, Biochem. Biophys. Res. Commun.,54, 628 (1973).
Rights and permissions
About this article
Cite this article
Yarygin, K.N., Nechaeva, N.V., Fateeva, V.I. et al. Circahoralian rhythm of cyclic AMP concentration in rat parotid gland slices. Bull Exp Biol Med 88, 1467–1469 (1979). https://doi.org/10.1007/BF00830364
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00830364