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The effect of partial and total extirpation of the cerebral cortex on the “mechanical secretion” of gastric juice

  • Pathological Physiology and General Pathology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The author studied the secretion of the gastric juice in response to mechanical stimulation of the stomach both in normal conditions and in partial and complete extirpation of the cortex of the large cerebral hemispheres. Complete extirpation of the cortex of the large cerebral hemispheres did not arrest the “mechanical secretion”.

On the contrary, in a majority of cases it caused a pronounced hypersecretory reaction. The latter is manifested in a sharp decrease of the latent period, rise in the amount of gastric juice, as well as by a certain increase of acidity and the digestive power of the mechanically-induced gastric secretion. This hypersecretion of the gastric juice may be considered to be the result of loss of the controlling cortical function on the activity of the subcortical autonomic centers.

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Chechulin, A.S. The effect of partial and total extirpation of the cerebral cortex on the “mechanical secretion” of gastric juice. Bull Exp Biol Med 45, 688–692 (1958). https://doi.org/10.1007/BF00824585

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  • DOI: https://doi.org/10.1007/BF00824585

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