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Selective N-propargylation of imidazole under microwave irradiation using some magnesium oxides as catalysts

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Abstract

The alkylation of imidazole (C3H4N2) with propargyl bromide (C3H3Br) using some magnesium oxides as catalysts under microwave irradiation was carried out with a high activity and selectivity. It has been found that it is possible to prepare efficiently N-alkyl derivatives of heterocycles under microwave irradiation in absence of solvent. Under these experimental conditions N-alkylated heterocycles can be obtained with higher selectivities than when using other basic media.

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References

  1. H. Pines and W.M. Stalick,Base-Catalyzed Reactions of Hydrocarbons and Related Compounds (Academic Press, London, 1977).

    Google Scholar 

  2. W.F. Hölderich, M. Hesse and F. Näumann, Ang. Chem. Int. Ed. 27 (1988) 226.

    Google Scholar 

  3. A. Corma, R.M. Martm-Aranda, V. Fornés and F. Key, J. Catal. 134 (1992) 58.

    Google Scholar 

  4. P. Laszlo,Preparative Chemistry using Supported Reagents (Academic Press, London, 1987).

    Google Scholar 

  5. W.F. Hölderich, in:Proc. 10th Int. Congr. on Catalysis, Budapest 1992, eds. L. Guczi, F. Solymosi and P. Tétényi (Akademiai Kiado, Budapest, 1993) p. 127.

    Google Scholar 

  6. E.V. Dehmlov and S.S. Dehmlov, in:Phase Transfer Catalysis, 2nd Ed. (Verlag Chemie, Weinheim, 1983.

    Google Scholar 

  7. A. Loupy, G. Bram and J. Sansoulet, New J. Chem. 16 (1992) 233.

    Google Scholar 

  8. D. Villemin, B. Labiad and A. Loupy, Synth. Commun. 23 (1993) 419.

    Google Scholar 

  9. D. Villemin, A. Ben Alloum and F. Thibault-Starzyk, Synth. Commun. 22 (1992) 1359.

    Google Scholar 

  10. A. Petit, A. Loupy, P. Maillard and M. Momenteau, Synth. Commun. 22 (1992) 1137.

    Google Scholar 

  11. B. Pilarski, Liebigs Ann. Chem. 6 (1983) 1078.

    Google Scholar 

  12. H. Galons, I. Bergerat, C. Combet-Farnoux, M. Miocque, G. Decodts and G. Bram, J. Chem. Soc. Chem. Commun. 23 (1985) 1730.

    Google Scholar 

  13. G. Bram, in:Chemical Reactions in Organic and Inorganic Constrained Systems, ed. R. Setton (Reidel, Dordrecht, 1986) pp. 191–196.

    Google Scholar 

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Authors and Affiliations

  1. Departamento de Química Inorgánica y Química Técnica (UNED), C/ Senda del Rey s/n, 28040, Madrid, Spain

    R. M. Martín-Aranda, M. L. Rojas-Cervantes, A. J. López-Peinado & J. de D. López-González

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  1. R. M. Martín-Aranda
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  2. M. L. Rojas-Cervantes
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  3. A. J. López-Peinado
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  4. J. de D. López-González
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Martín-Aranda, R.M., Rojas-Cervantes, M.L., López-Peinado, A.J. et al. Selective N-propargylation of imidazole under microwave irradiation using some magnesium oxides as catalysts. Catal Lett 25, 385–392 (1994). https://doi.org/10.1007/BF00816318

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  • DOI: https://doi.org/10.1007/BF00816318

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