Summary
The intermolecular interactions of biliverdin with apomyoglobin were investigated using UV-VIS spectroscopy and chiroptical methods. Biliverdin is bound reversibly in the heme pocket of the apoprotein. The structural implications of the spectroscopic findings are discussed.
Zusammenfassung
Die intermolekularen Wechselwirkungen von Biliverdin mit Apomyoglobin wurden mittels UV-VIS-Spektroskopie und chiroptischen Methoden untersucht. Biliverdin wird reversibel in der Häm-Tasche des Apoproteins gebunden. Strukturelle Implikationen der spektroskopischen Resultate werden diskutiert.
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Marko H., Müller N., Falk H. (1989) Monatsh. Chem.120: 163
Huber R., Schneider M., Mayr I., Müller R., Deutzmann R., Suter F., Zuber H., Falk H., Kayser H. (1987) J. Mol. Biol.198: 499
Scheer H. (1981) Angew. Chem.93: 230
Schirmer T., Bode W., Huber R., Sidler W., Zuber H. (1985) J. Mol. Biol.184: 257
Schirmer T., Bode W., Huber R. (1987) J. Mol. Biol.196: 677
Blauer G. (1986) Biochim. Biophys. Acta884: 602
Boxer S. G., Wright K. A. (1979) J. Amer. Chem. Soc.101: 6791
McDonagh A. F., Palma L. A. (1980) Biochem. J.189: 193
Teale F. W. J. (1959) Biochim. Biophys. Acta35: 43
Gattermann L., Wieland T. (1982) Die Praxis des Organischen Chemikers. De Gruyter, Berlin New York, p. 694
Vosburgh W. G., Cooper G. R. (1941) J. Amer. Chem. Soc.63: 437
Falk H., Gsaller H., Hubauer E., Müller N. (1985) Monatsh. Chem.116: 939
Hug W., Wagnière G. (1972) Tetrahedron28: 1241
Falk H., Thirring K. (1981) Tetrahedron37: 761
Krois D., Lehner H. (1987) J. Chem. Soc. Perkin Trans. II: 1523
Lind K. E., Møller J. V. (1976) Biochim. Biophys. Acta155: 669
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Marko, H., Müller, N. & Falk, H. Complex formation between biliverdin and apomyoglobin. Monatsh Chem 120, 591–595 (1989). https://doi.org/10.1007/BF00810847
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DOI: https://doi.org/10.1007/BF00810847