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Effect of predisposition to mammary gland tumors on lactate dehydrogenase isoenzyme spectrum in the mouse ovary

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

More intensive synthesis of the M-subunits of lactate dehydrogenase was demonstrated biochemically in the ovaries of mice with a high predisposition to cancer than in animals with a low predisposition, although in both strains of mice the common direction of glycolysis in the ovary was aerobic. Differences in the activity of M-and H-subunits of the enzyme were detected histochemically in the various structures of the ovary in intact animals and in mice receiving hexestrol.

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Zaretskaya, I.S., Boikova, V.I., Tereshchenko, I.P. et al. Effect of predisposition to mammary gland tumors on lactate dehydrogenase isoenzyme spectrum in the mouse ovary. Bull Exp Biol Med 78, 1399–1401 (1974). https://doi.org/10.1007/BF00808716

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  • DOI: https://doi.org/10.1007/BF00808716

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