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Zur Kenntnis der gemeinsamen Einwirkung von elementarem Selen und gasförmigem Ammoniak bzw. Ethylenimin auf Ketone

On the joint reaction of elemental selenium with gaseous ammonia and ethylenimine, respectively in the presence of ketones. Joint reaction of elementary sulfur and gaseous ammonia with ketones, 96

Über die gemeinsame Einwirkung von elementarem Schwefel und gasförmigem Ammoniak auf Ketone, 96. Mitt.

  • Organische Chemie Und Biochemie
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Abstract

Elemental sulfur reacts with ketones and gaseous ammonia at room temperature yielding thiazoline-3 in excellent yields. Under the same conditions elemental selenium does not react at all. Attempts using the known techniques which have been applied in improving the reactivity of slowly reacting ketones in thiazoline-3-synthesis have been unsuccessful (Exp. No. 1–17). The reaction of α-halogenketones with sodiumhydrogenselenide to synthesize α-hydroselenoketones gives only the original ketones and selenium in almost quantitative yields (No. 18–23). The same is observed with α-haloketones and sodium ore magnesium-diselenides (No. 24–45). The explanation of these unexpected results is the strong reducing power of the hydrogenselenide (No. 46–52). Even α-bromoketones with activated bromine (i.g. by phenyl groups) were reduced by sodiumhydrogensulfide giving red undefinite oils. However, α-chloroketones give α-mercaptoketones in excellent yields (No. 53–61). Hydrogenselenide reduces α-mercaptoketones to sulfur and ketones in the presence of triethylamine (No. 62–67). Also the transformation of α-selenocyanketones to α,α′-diketodisenides by alkali or the oxidative hydrolysis of selenium-“BUNTE” salts does not work and gives elementary selenium only. Studies about the concomitant reaction of elementary selenium and ethylenimine on ketones were continued (No. 68–82).

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  1. Institut für Technische Chemie und Petrolchemie, Rheinisch-Westfälische Technische Hochschule Aachen, D-5100, Aachen, Bundesrepublik Deutschland

    Friedrich Asinger & Maria Karoline Schmitz

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  1. Friedrich Asinger
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Asinger, F., Schmitz, M.K. Zur Kenntnis der gemeinsamen Einwirkung von elementarem Selen und gasförmigem Ammoniak bzw. Ethylenimin auf Ketone. Monatsh Chem 113, 1191–1212 (1982). https://doi.org/10.1007/BF00808632

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