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Content of prostaglandins and cyclic AMP in rat tissue

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The content of prostaglandins (PG) and cyclic adenosine-3′,5′-monophosphate (cyclic AMP) in rat tissues was studied by a radioisotope method. The maximal content of both PG and cyclic AMP was found in the same organs, those functioning most actively: the brain, endocrine glands, and small intestine, and the minimal content in adipose tissue. The investigations show close functional interdependence between PG synthesis and adenylate cyclase activity in the tissues of the body.

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Literature Cited

  1. L. N. Bernshtein, Usp. Fiziol. Nauk, No. 2, 111 (1975).

    Google Scholar 

  2. V. P. Komissarenko, V. N. Slavnov, E. V. Épshtein, et al., Klin. Med., No. 4, 22 (1976).

    Google Scholar 

  3. N. H. Andersen and P. W. Ramwell, Arch. Int. Med.,133, 30 (1974).

    Google Scholar 

  4. G. D. Aurbach and B. A. Houston, J. Biol. Chem.,243, 5935 (1968).

    Google Scholar 

  5. G. Burke, Am. J. Physiol.,218, 1445 (1970).

    Google Scholar 

  6. R. W. Butcher and C. E. Baird, J. Biol. Chem.,243, 1713 (1966).

    Google Scholar 

  7. R. W. Butcher and E. W. Sutherland, Ann. N. Y. Acad. Sci.,139, 849 (1967).

    Google Scholar 

  8. G. H. Juvenas, D. Nuteren, R. Beerthuis, et al., Biochim. Biophys. Acta,202, 231 (1970).

    Google Scholar 

  9. T. Koneko and J. B. Field, J. Lab. Clin. Med.,74, 682 (1969).

    Google Scholar 

  10. F. Kuehl, J. Humes, et al., Science,169, 883 (1970).

    Google Scholar 

  11. T.-Ch. Peng, K. M. Six, and P. L. Munson, Endocrinology,86, 202 (1970).

    Google Scholar 

  12. A. Steiner, A. Pagliara, L. Chase, et al., J. Biol. Chem.,247, 1114 (1972).

    Google Scholar 

  13. K. Taya, T. Sato, and M. Igarashi, Endocrinol. Jpn.,22, 131 (1975).

    Google Scholar 

  14. U. Zor, T. Koneko, T. Lowe, et al., J. Biol. Chem.,244, 5189 (1969).

    Google Scholar 

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Authors and Affiliations

  1. Academy of Sciences of the Ukrainian SSR, Ukraine

    V. P. Komissarenko

Authors
  1. V. P. Komissarenko
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  2. V. N. Slavnov
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  3. E. V. Épshtein
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  4. V. D. Malinkovich
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Additional information

Kiev Scientific-Research Institute of Endocrinology and Metabolism. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 4, pp. 416–418, April, 1977.

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Komissarenko, V.P., Slavnov, V.N., Épshtein, E.V. et al. Content of prostaglandins and cyclic AMP in rat tissue. Bull Exp Biol Med 83, 480–482 (1977). https://doi.org/10.1007/BF00807482

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  • DOI: https://doi.org/10.1007/BF00807482

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