Abstract
The effect of inhibitors of serotonin and noradrenalin synthesis in the brain on learning in rats with emotionally different reinforcement was investigated. Parachlorophenylalanine (320 mg/kg) impaired learning in rats with food reinforcement but improved learning with pain reinforcement. Disulfiram (100 mg/kg) which significantly impaired learning with pain reinforcement, had no effect on learning with food reinforcement, α-Methyl-m-tyrosine inhibited both forms of learning. Comparison of these facts with previous observations confirms the hypothesis that the monoaminergic systems of the brain play the role of intermediary between the emotions and memory.
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Semenova, T.P., Vekshina, N.L. Effect of inhibitors of serotonin and noradrenalin synthesis on learning in rats with emotionally different reinforcement. Bull Exp Biol Med 85, 701–703 (1978). https://doi.org/10.1007/BF00806140
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DOI: https://doi.org/10.1007/BF00806140