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Migrating ability of tumor cells treated with immune sera

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The action of antitumor sera (ATS) on the adhesive properties of L cells and of Ehrlich's ascites carcinoma cells was studied. The ability of the tumor cells to adhere to plastic and glass and to form rosettes with sheep's red blood cells was reduced after treatment with immune serum and, when injected into mice, fewer of these cells were held up in the lungs, spleen, and liver. The results show that antibodies may play an essential role in the metastasization of tumor cells.

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Lebedev, K.A., Kaulen, D.R., Khorobrykh, V.V. et al. Migrating ability of tumor cells treated with immune sera. Bull Exp Biol Med 84, 1753–1755 (1977). https://doi.org/10.1007/BF00804827

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  • DOI: https://doi.org/10.1007/BF00804827

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