Skip to main content
Log in

Investigation of the properties of a hyaluronidase preparation isolated from the female reproductive system

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

At a certain period of the sex cycle an enzyme with hyaluronidase action is secreted by the female reproductive system (oviducts and uterus); its activity is highest during the period of estrus. The possible role of the hyaluronidase of the oviduct in the physiology of fertilization is postulated. A new source for obtaining hyaluronidase preparations, the uterine mucosa of sexually mature animals, is suggested. These preparations have specific activity and are nontoxic.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. A. A. Baev, Biokhimiya, No. 2, 328 (1964).

    Google Scholar 

  2. S. M. Bychkov, Uspekhi Sovr. Biol.,27, No. 3, 479 (1949).

    Google Scholar 

  3. B. S. Kaplanskii, Current Problems in Biochemistry [in Russian], Vol. 2, Moscow (1962), p. 203.

    Google Scholar 

  4. B. S. Kasavina, G. M. Belen'kaya, and I. N. Shinkarenko, Sov. Med., No. 4, 103 (1959).

    Google Scholar 

  5. L. I. Magracheva, Akush. i Gin., No. 4, 43 (1957).

    Google Scholar 

  6. R. V. Merkur'eva, Glycosaminoglycans and Glycoproteins in Some Diseases and Injuries of the Locomotor System. Author's Abstract of Doctoral Dissertation, Moscow (1973).

  7. R. V. Merkur'eva, in: Biochemical Investigations in Traumatology and Orthopedics [in Russian], Moscow (1973), p. 71.

  8. M. Sh. Mogilevskii-Gurvich, Experimental Investigations of the Hyaluronidase-Hyaluronic Acid System and Its Role in Pathology. Author's Abstract of Doctoral Dissertation, Leningrad (1969).

  9. Yu. V. Natochin, Byull. Éksperim. Biol. i Med., No. 8, 118 (1959).

    Google Scholar 

  10. N. T. Plishko et al., in Proceedings of the 4th and 7th All-Union Conferences on the Physiological and Biochemical Bases of Increasing the Productivity of Livestock [in Russian], Book 2, Borovsk (1966), p. 196; Borovsk (1970), p. 330.

  11. N. T. Plishko, Author's Certificate No. 302123. Otkrytiya, No. 15 (1971).

  12. A. B. Preisman, Akush. i Gin., No. 3, 102 (1960).

    Google Scholar 

  13. M. B. Rozumenko, The State and Role of the Hyaluronidase Enzyme System during Pregnancy and Parturition with a Pharmacological and Complicated Course. Author's Abstract of Doctoral Dissertation, Khar'kov (1970).

  14. E. M. Smirnova, Trudy Leningrad. Nauch.-Issled. Inst. Vaktsin i Syvorotok,6, 96 (1967).

    Google Scholar 

  15. Technological Instructions for the Production of Meat and Meat Products, Section 12. Organic Preparations [in Russian], Moscow (1961), p. 147.

  16. B. P. Khvatov, Arkh. Anat., No. 4, 7 (1954).

    Google Scholar 

  17. W. Bonner and J. Cantey, Clin. Chim. Acta,13, 746 (1966).

    Google Scholar 

  18. S. F. Jackson, Proc. Roy. Soc. B.,175, 405 (1970).

    Google Scholar 

  19. G. K. Lukacs, L. Modis, I. Földes, et al., in: Mechanisms of Regeneration of Bone Tissue [in Russian], Moscow (1972), p. 222.

  20. J. L. Reissing, J. L. Strominger, and L. F. Leloir, J. Biol. Chem.,217, 959 (1955).

    Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Plishko, N.T., Merkur'eva, R.V. Investigation of the properties of a hyaluronidase preparation isolated from the female reproductive system. Bull Exp Biol Med 78, 1329–1331 (1974). https://doi.org/10.1007/BF00804375

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00804375

Key words

Navigation