Abstract
The duration of the mitotic cycle on the 2nd, 5th, 8th, and 11th–12th day of development of the ascites variant and on the 10th and 15th days of development of the solid variant of hepatoma 22A was determined by an autoradiographic method in the cells of this tumor. The duration of the mitotic cycle of the cells of the ascites variant was found to increase considerably during the life of this strain (the duration of the S-period increased from 14 to 26–27 h and of the G2-period from 2.2 to 13 h). The duration of the mitotic cycle in cells of the solid variant of hepatoma 22A was the same at both times of development of this tumor. Correlation was found between changes in the duration of the mitotic cycle during the life of the strain of tumor cells and its changes with an increase in the period after the first passage of that strain.
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Belyaeva, I.D., Ivleva, T.S. Mitotic cycles of hepatoma 22A cells. Bull Exp Biol Med 78, 937–939 (1974). https://doi.org/10.1007/BF00803934
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DOI: https://doi.org/10.1007/BF00803934