Abstract
Starting from the day after operation, partly hepatectomized rats receivined thyroid or triiodothyronine separately or in conjunction with theophylline, by mouth. Thyroid and the thyroid hormone increased the oxygen consumption but considerably reduced the glycogen content of the liver. No statistically significant increase in the degree of regeneration hypertrophy, studied on the 7th day after the operation, was produced by these preparations. In conjunction with theophylline they increased the absolute and relative weight of the regenerating liver. The absolute weight of the liver was increased by 19–36%. The DNA content, the number of nuclei, and the number of binuclear cells were indistinguishable from the control.
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Vunder, V.P. Effect of thyroid extract and triiodothyronine, with or without the addition of theophylline, on regeneration of the liver in rats. Bull Exp Biol Med 78, 928–930 (1974). https://doi.org/10.1007/BF00803931
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DOI: https://doi.org/10.1007/BF00803931