Abstract
The proliferative activity of hematopoietic stem cells was studied by the “thymidine suicide” method in organ cultures of mouse embryonic liver. Hematopoiesis was found to continue in these cultures for 2 months. The rate of proliferation starts to fall off only on the 50th day of culture; at the same time there is a sharp decrease in the number of residual hematopoietic stem cells in the cultures.
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Rudneva, N.A. Proliferative activity of hematopoietic stem cells in long-term cultures of mouse embryonic liver. Bull Exp Biol Med 78, 923–924 (1974). https://doi.org/10.1007/BF00803929
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DOI: https://doi.org/10.1007/BF00803929