Abstract
Experiments on dogs showed that if the specific adrenergic receptors of the blood vessel wall (α- and β-receptors) were blocked by phentolamine or inderal it still continued to produce tissue blood clotting factors after stimulation of the vagus nerve. No response of this type was observed to stimulation of the nerve after the cholinergic receptors had been blocked by atropine. It is concluded that hyperfibrinolysis and hypercoagulation developing after vagus nerve stimulation are due to excitation of cholinergic structures.
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Mishchenko, V.P. Role of specific adrenergic and cholinergic receptors of the blood vessel wall in the regulation of blood clotting during stimulation of the vagus nerve. Bull Exp Biol Med 78, 858–861 (1974). https://doi.org/10.1007/BF00803908
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DOI: https://doi.org/10.1007/BF00803908