Abstract
During forced breathing there is too little time for uniform mixing of the inspired gas by diffusion with the gas remaining in the lungs after expiration, the unevenness of ventilation increases, and this is manifested as a marked increase in the steepness of rise of the alveolar plateau on the nitrogen concentration curve obtained by the single-breath technique (oxygen is used as the test gas; the nitrogen concentration is recorded). The respiratory dead space is considerably increased during forced breathing.
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Sidorenko, L.A., Vinitskaya, R.S. & Shik, L.L. Mixing of gases in the lungs by diffusion. Bull Exp Biol Med 78, 852–854 (1974). https://doi.org/10.1007/BF00803906
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DOI: https://doi.org/10.1007/BF00803906