Abstract
The function of the respiratory system is to remove carbon dioxide from, and add oxygen to, venous blood flowing through the pulmonary circulation. The system accomplishes this by two interrelated processes: gas exchange and ventilation. We will discuss these two concepts in detail. Additional topics covered in this chapter include: alveolar microanatomy, oxygen delivery, alveolar gas equation, carbon dioxide elimination, ventilation-perfusion matching, gas diffusion, pulmonary elasticity, compliance, surface tension, law of Laplace, pressure-volume curves, functional residual capacity, inspiration, expiration, airway resistance, and Poiseuille’s law.
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References
West JB. Respiratory physiology: the essentials. 9th ed. Philadelphia: Lippincott Williams & Wilkins; 2012.
Kreit JW. Gas exchange. In: Mechanical ventilation: physiology and practice. Oxford: Oxford University Press; 2017. https://doi.org/10.1093/med/9780190670085.003.0002.
Wagner PD, Laravuso RB, Uhl RR, West JB. Continuous distributions of ventilation-perfusion ratios in normal subjects breathing air and 100 percent O2. J Clin Invest. 1974;54(1):54–68.
Kreit JW. Respiratory mechanics. In: Mechanical ventilation: physiology and practice. Oxford: Oxford University Press; 2017. https://doi.org/10.1093/med/9780190670085.003.0001.
Macklem PT, Permutt S. The lung in the transition between health and disease. 1st ed. New York: Marcel Dekker; 1979.
Cavagna G. Fundamentals of human physiology. 1st ed. Cham: Springer Nature; 2019.
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Do, K., Musch, G. (2022). Basic Physiology of Respiratory System: Gas Exchange and Respiratory Mechanics. In: Bellani, G. (eds) Mechanical Ventilation from Pathophysiology to Clinical Evidence. Springer, Cham. https://doi.org/10.1007/978-3-030-93401-9_1
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DOI: https://doi.org/10.1007/978-3-030-93401-9_1
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