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Analysis of cutaneous reception of pressure in man using the method of conditioned vascular reflexes

Communication IV. The effect of various pharmacologic substances on the character of conditioned vascular reactions developed to barostimulation of the skin

  • Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The author studied the effect of bromide and phenamine (benzedrine), which act selectively on the processes of inhibition and excitation in the cortex, on conditioned vascular reflexes to loads and to the intensity of perception of the barostimuli. Bromine caused inhibition of conditioned and unconditioned vascular reflexes to loads and decreased the intensity of perception of weights. Phenamine in the dose of 0.02 g also caused inhibition of unconditioned and conditioned vascular reflexes to weights in 2 cases and weakened the intensity of sensation. In lower doses, phenamine increased the vascular conditioned reflexes. In one case with a weaker excitability, phenamine in the dose of 0.02 g considerably increased the vascular conditioned reflexes to weights. Vascular conditioned reflexes to weight which were disturbed by bromide and phenamine returned to normal at the end of each experiment. This took place in all cases, although the pharmacological agent decreasing the excitation of the cerebral cortex was till present in the organism.

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Fel'berbaum, R.A. Analysis of cutaneous reception of pressure in man using the method of conditioned vascular reflexes. Bull Exp Biol Med 45, 263–267 (1958). https://doi.org/10.1007/BF00803325

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  • DOI: https://doi.org/10.1007/BF00803325

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