Abstract
Hypoinsulinemia in the superior pancreatico-duodenal vein and depression of the first phase of insulin secretion by the pancreas, characteristic of alloxan diabetes of different degrees of severity, are not observed in the femoral vein. The results of an investigation of the dynamics of the insulin and glucose concentrations in the superior pancreatico-duodenal vein emphasize the dominant role of the pancreatic factor in the pathogenesis of alloxan diabetes in dogs. Data obtained by the study of these indices in the peripheral femoral vein do not reflect this state of affairs adequately.
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Dagaeva, L.N., Belikova, F.S., Podotykina, O.I. et al. Dynamics of insulin secretion in dogs with alloxan diabetes. Bull Exp Biol Med 85, 289–292 (1978). https://doi.org/10.1007/BF00801337
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DOI: https://doi.org/10.1007/BF00801337