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Circadian rhythms in connective tissue

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The study of circadian rhythms in rat connective tissue showed that its cells (especially histiocytes) are characterized by circadian rhythms of their metabolic processes. This is manifested as a distinct diurnal dynamic of succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH) activity. During adaptation to high-altitude hypoxia SDH and LDH activity was appreciably higher than in the control but the dynamics of changes in the activity of these enzymes during the 24-h period was similar in its general features to that in the control group. It is postulated that circadian metabolic rhythms in connective tissues are relatively stable: They show no sign of breaking down during adaptation to high-altitude conditions.

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Authors
  1. V. A. Isabaeva
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  2. N. N. Mikhaliot
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  3. V. I. Frolenko
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Isabaeva, V.A., Mikhaliot, N.N. & Frolenko, V.I. Circadian rhythms in connective tissue. Bull Exp Biol Med 81, 254–256 (1976). https://doi.org/10.1007/BF00801088

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  • DOI: https://doi.org/10.1007/BF00801088

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