Skip to main content
Log in

Histochemical investigation of the distribution of plasminogen activator in experimental ischemia

  • Pathophysiology and General Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Experimental ischemia induced in rats by ligation of the coronary artery leads to a decrease in the concentration of plasminogen activator in the myocardial tissues, especially in the zone of necrosis 1 day after ligation of the vessel. After 3 days the concentration of plasminogen activator is restored. The results of the histochemical tests were confirmed by biochemical analysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. A. K. Ageev, Histochemistry of Alkaline and Acid Phosphatases in Man in Health and Disease [in Russian], Leningrad (1969).

  2. G. V. Andreenko and L. A. Migalina, Biokhimiya, No. 4, 685 (1971).

    Google Scholar 

  3. A. I. Strukov, E. F. Lushnikov, and K. A. Gornak, The Histochemistry of the Myocardial Infarct [in Russian], Moscow (1967).

  4. B. L. Movshovich and V. P. Mishurova, Kardiologiya, No. 2, 32 (1974).

    Google Scholar 

  5. H. C. Kwaan and T. Astrup, Arch. Path.,76 595 (1963).

    Google Scholar 

  6. H. C. Kwaan and T. Astrup, Thrombos, Diath. Haemorrh. (Stuttgart),17, 407 (1964).

    Google Scholar 

  7. H. C. Kwaan, T. Astrup, and F. Games, Clin. Res.,13, 212 (1965).

    Google Scholar 

  8. H. C. Kwaan and T. Astrup, Lab. Invest.,17, 140 (1967).

    Google Scholar 

  9. M. Pandolfi, in: International Symposium on Tissue Factors in the Homeostasis of Coagulation — Fibrinolysis System, Florence (1967), p. 326.

  10. B. Rabinowitz, M. Kligerman, and W. W. Parmley, Am. J. Cardiol.,34, 7 (1974).

    Google Scholar 

  11. L. Rejniak, J. Prokopowicz, S. Niewiarowski, et al., Folia Histochem. Cytochem.,4, 325 (1966).

    Google Scholar 

  12. A. S. Todd, Nature,181, 495 (1958).

    Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Andreenko, G.V., Podorol'skaya, L.V. & Lyutova, L.V. Histochemical investigation of the distribution of plasminogen activator in experimental ischemia. Bull Exp Biol Med 81, 160–162 (1976). https://doi.org/10.1007/BF00801056

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00801056

Key words

Navigation