Abstract
The kinetics of hematopoietic, stem cells was studied in organ culture of a suspension of mouse embryonic liver grown directly on filters and on a previously grown embryonic thymic feeder. In the first two weeks of culture, hematopoiesis in the suspension was virtually indistinguishable from hematopoiesis in fragments of the same age and the same time of culture, whereas later hematopoiesis was more active in the suspension grown on thymic feeder. The possible role of the thymus in hematopoiesis is discussed.
Similar content being viewed by others
Literature Cited
E. A. Luria, Dokl. Akad. Nauk SSSR,171, 1431 (1966).
T. E. Manakova, Probl. Gematol., No. 11, 26 (1974).
N. A. Rudneva and N. L. Samoilina, Probl. Gematol., No. 10, 34 (1973).
R. Schofield and L. G. Lajtha, Probl. Gematol., No 10, 55 (1973).
T. M. Dexter, T. D. Allen, L. G. Lajtha, et al., J. Cell. Physiol.,82, 461 (1973).
J. W. Goodman and S. G. Shinpock, Proc. Soc. Exp. Biol. (New York),129, 417 (1968).
B. I. Lord and R. Schofield, Blood,42, 395 (1973).
Rights and permissions
About this article
Cite this article
Manakova, T.E. Effect of thymic feeder on kinetics of hematopoietic stem cells in a suspension of mouse embryonic liver. Bull Exp Biol Med 79, 571–573 (1975). https://doi.org/10.1007/BF00800506
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00800506