Abstract
An investigation of the cerebral circulation by the thermoelectric method showed that stimulation of the cervical sympathetic nerve leads to considerable changes in the blood supply to the brain. The changes in blood flow are biphasic in character: An initial small increase is followed by a decrease below the original level. Pharmacological analysis with α and β adrenoblockers showed that the constrictor response of the cerebral vessels is due to excitation of α-adrenergic structures and the dilator response to excitation of β-adrenergic structures. A possible mechanism of these changes is postulated.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
S. A. Bugaev, Vestn. Akad. Med. Nauk SSSR, No. 12, 38 (1973).
M. D. Gaevoi, Fiziol. Zh. SSSR, No. 11, 1677 (1971).
B. N. Klosovskii, The Circulation of Blood in the Brain [in Russian], Moscow (1951).
A. V. Tonkikh and Yu. A. Borkovskaya, Fiziol. Zh. SSSR, No. 7, 1001 (1972).
R. P. Ahlquist, Am. J. Physiol.,153, 586 (1948).
H. S. Forbes and S. S. Cobb, Brain,61, 221 (1938).
A. M. Harper, V. D. Deshmukh, I. O. Rowan, et al., Arch. Neurol. (Chicago),27, 1 (1972).
B. Holmqvist, D. Ingvar, and B. Siedjo, Acta Physiol. Scand.,40, 146 (1957).
D. H. Ingvar and N. A. Lassen, Triangle,9, 234 (1970).
I. M. James, R. A. Millar, and M. J. Purves, Circulat. Res.,25, 77 (1969).
A. Juhasz-Nagy and G. Bock, Experientia,29, 675 (1973).
N. Ludwigs and M. Schneider, Pflüg. Arch. Ges. Physiol.,259, 43 (1954).
G. Oberdörster, R. Lang, and R. Zimmer, Pflüg. Arch. Ges. Physiol.,340, 145.
C. F. Schmidt, Am. J. Physiol.,114, 572 (1936).
Rights and permissions
About this article
Cite this article
Bugaev, S.A. Role of adrenergic structures in functional control over the cerebral circulation. Bull Exp Biol Med 81, 9–12 (1976). https://doi.org/10.1007/BF00800151
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00800151