Abstract
Injection of heterologous red cells was shown to lead after 15 min to the displacement of noradrenalin from efferent nerve endings, to a marked reorganization of the metabolism of the central follicular cells and the peripheral monoamine-containing cells of the marginal sinuses of the spleen, and cortical luminescent and mast cells of the thymus. Inversion of the medullary substance into the cortex was observed in the thymus. These changes increased in intensity until 2 h.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
A. D. Ado, Antigens as Extraordinary Stimuli of the Nervous System [in Russian], Moscow (1952).
F. Burnet, Cellular Immunology, Cambridge University Press, New York (1969).
V. V. Vinogradov and N. F. Vorob'eva, Arkh. Pat., No. 4, 18 (1972).
A. N. Gordienko, The Nervous Reflex Mechanism of Antibody Production and the Regulation of Phagocytosis [in Russian], Moscow (1954).
D. F. Gordon, E. A. Nuzhnenko, V. I. Smirnova, et al., Byull. Éksp. Biol. Med., No. 12, 105 (1972).
D. F. Gordon, in: Reactivity and Plasticity of the Epithelium and Connective Tissue under Normal, Experimental, and Pathological Conditions [in Russian], Sverdlovsk (1974), p. 44.
D. F. Gordon, I. G. Zelenova, Z. I. Mikheeva, et al., in: Neurohumoral and Pharmacological Correction of Experimental and Clinical Immunologic Reactions [in Russian], Leningrad (1975), p. 15.
E. V. Gruntenko, Immunity and the Onset of Malignant Tumors [in Russian], Novosibirsk (1977).
L. V. Devoino, in: The Physiology and Biochemistry of Amines [in Russian], Moscow (1969), pp. 242–246.
E. A. Korneva, in: Neurohumoral and Pharmacological Correction of Experimental and Clinical Immunologic Reactions [in Russian], Leningrad (1975), p. 36.
E. M. Krokhina and P. N. Aleksandrov, Kardiologiya, No. 3, 97 (1969).
V. E. Sergeeva, K. S. Dzamashvili, and G. M. Timofeeva, Arkh. Anat., No. 6, 56 (1974).
E. P. Frolov, Neurohumoral Mechanisms of Regulation of Immunologic Processes [in Russian], Moscow (1974).
P. Alm et al., Acta Physiol. Scand.,76, 106 (1969).
B. Falck, N. A. Hillarp, G. Thieme, et al., J. Histochem. Cytochem.,10, 348 (1962).
Rights and permissions
About this article
Cite this article
Gordon, D.S., Sergeeva, V.E. & Golubeva, N.N. Activity and distribution of biogenic amines in structures of the thymus and spleen in response to injection of isologous and heterologous red cells. Bull Exp Biol Med 86, 1109–1112 (1978). https://doi.org/10.1007/BF00799607
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00799607