Abstract
Bordetella pertussis cells and some of their components, if injected into mice, cause an increase in the DNA-binding activity of their sera detectable at the ionic strength of physiological saline mainly on the 14th day. The inhibition method showed that interaction of the sera with native DNA is specific. The maximal increase in the content of serum protein reacting with DNA in solutions of low ionic strength (0.05 M NaCl) was observed on the seventh day. However, after injection ofB. pertussis cells and their cytoplasmic membranes the increased content of DNA-binding proteins continued until the 14th day.
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Moskalenko, E.P., Il'ina, S.I., Podgorodnichenko, V.K. et al. Induction of antibodies against native DNA by components of Bordetella pertussis. Bull Exp Biol Med 86, 1079–1081 (1978). https://doi.org/10.1007/BF00799597
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DOI: https://doi.org/10.1007/BF00799597