Abstract
Some functional properties of interferon and of a factor inhibiting migration of macrophages (MMIF), obtained by stimulation of human tonsillar lymphocytes by Newcastle disease virus (NDV) or streptolysin O, were investigated. Both interferon and MMIF were shown to inhibit migration of human tonsillar cells actively, but they differed in their antiviral activity and their sensitivity to heating to 56°C for 30 min, MMIF production reached its maximum later than interferon production. Stimulation of human tonsillar lymphocytes by NDV led to the production of a broader spectrum of mediators of hypersensitivity of delayed type than stimulation by streptolysin O.
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Mel'nikov, O.F., Krivokhatskaya, L.D. & Povolotskii, Y.L. Comparative assessment of the properties of macrophage migration inhibiting factor and of interferon. Bull Exp Biol Med 83, 343–345 (1977). https://doi.org/10.1007/BF00799357
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DOI: https://doi.org/10.1007/BF00799357