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Effect ofShigella sonnei endotoxin on the cholinergic control of the intestinal circulation

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect ofShigella sonnei endotoxin on the cholinergic control of the cardiovascular system was studied by an extracorporeal autoperfusion method with resistography of the intestinal vessels and synchronous multichannel recording of the parameters of the systemic circulation in experiments onMacaca rhesus. The development of toxemia was shown to be accompanied by changes in the cholinergic regulation and subsequent disturbance of the intestinal and systemic circulation. It is suggested that damage to cholinergic regulatory structures and disturbance of the circulation determine the development and course of the infectious process.

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Galaguza, Y.P. Effect ofShigella sonnei endotoxin on the cholinergic control of the intestinal circulation. Bull Exp Biol Med 83, 302–304 (1977). https://doi.org/10.1007/BF00799343

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  • DOI: https://doi.org/10.1007/BF00799343

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