Abstract
Transplatation of bone marrow cells mixed with allogeneic T lymphocytes into irradiated recipients is accompanied by inactivation of stem cells of the graft. Lymphocytes from lymph nodes of T mice possess greater inactivating power than T lymphocytes from the spleen. In the case of the combined action of T lymphocytes from the spleen and T lymphocytes from the lymph nodes, inactivation of the stem cells was slight in degree or absent altogether.
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Ignat'eva, G.A., Man'ko, V.M. & Rudneva, T.B. Inactivation of stem cells by allogeneic lymphocytes: competition between T1 and T2 subpopulations. Bull Exp Biol Med 83, 841–843 (1977). https://doi.org/10.1007/BF00798892
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DOI: https://doi.org/10.1007/BF00798892