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The dynamics of the functional state of the neuromuscular apparatus in experimental tumors

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

To assess the functional state of the neuromuscular apparatus in experimental homotransplanted tumors in mice and rats a study was made of the motor chronaxie electroexcitability curve and physiological lability. After transplantation of Ehrlich's carcinoma to mice and of lymphosarcoma to rats marked changes occur in the functional state of the motor apparatus. Reduction of physiological lability is observed already during the pretumoral period. With growth of the tumors and development of cachexie there is a progressive reduction of excitability and lability, disturbance of correlations between the strength of the stimulus and the muscular response, development of equalizing and paradoxical phases-parabiosis.

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Authors and Affiliations

  1. Department of Pathological Physiology, Kemerovo Medical Institute, Kemerovo, USSR

    A. I. Plaksin & A. Ya. Evtushenko

Authors
  1. A. I. Plaksin
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  2. A. Ya. Evtushenko
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Plaksin, A.I., Evtushenko, A.Y. The dynamics of the functional state of the neuromuscular apparatus in experimental tumors. Bull Exp Biol Med 55, 203–206 (1964). https://doi.org/10.1007/BF00798832

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  • DOI: https://doi.org/10.1007/BF00798832

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