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The significance of the lymphoid apparatus of the bronchial tree in the development of leukemic foci in the lungs associated with transplanted leukemia in mice

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

In studying the transplantable hemocytoblastic leukemia in mice changes in the lungs were traced from the 1st to the 12th day of the development of this affection. As a rule, no leukemic infiltrates occurred in the lungs in leukemia of affected mice. Leukemic infiltrates from hemocytoblasts are formed only in cases when there is a marked hyperplasia of lymphoid follicles of the bronchial tree in the presence of inflammatory process in the lungs. Leukemic infiltrates are nestlike in nature, are located in the usual sites of lymphoidal accumulations and with a partial atelectasis of the lungs may acquire a pseudodiffuse appearance. There was no conformity between the development of leukemic changes in the transplantation focus and in the pulmonary tissue.

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Literature Cited

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Authors and Affiliations

  1. Department of Pathological Anatomy, I. P. Pavlov Ist Leningrad Medical Institute, Leningrad, USSR

    F. B. Ermakova

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  1. F. B. Ermakova
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Ermakova, F.B. The significance of the lymphoid apparatus of the bronchial tree in the development of leukemic foci in the lungs associated with transplanted leukemia in mice. Bull Exp Biol Med 55, 194–197 (1964). https://doi.org/10.1007/BF00798830

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  • DOI: https://doi.org/10.1007/BF00798830

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