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Role of injury in the appearance of “activated” smooth muscle cells

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In experiments on rats the ultrastructure of the muscle tissue of the inferior vena cava after disturbance of the outflow of blood, of the muscular coat of the stomach after resection of 50% of its fundus, and of the muscular coat of the cecum after constriction of its ascending portion was studied. “Activation” of smooth muscles was shown to reflect the phase of injury to the ultrastructure of the cells, followed by processes of intracellular regeneration. Analysis of the ratio between DNA-synthesizing and “activated” cells showed the local origin of the latter from differentiated myocytes.

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Kaufman, O.Y., Perov, Y.L., Boikov, A.K. et al. Role of injury in the appearance of “activated” smooth muscle cells. Bull Exp Biol Med 84, 1053–1056 (1977). https://doi.org/10.1007/BF00798545

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  • DOI: https://doi.org/10.1007/BF00798545

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