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Studies on pyrazinyl-pyrazylidene tautomerism of pyrazine-acetonitrile derivatives

Untersuchungen über die Pyrazinyl-Pyraziliden-Tautomerie von Pyrazinacetonitril-Derivaten

  • Organische Chemie Und Biochemie
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Abstract

The equilibria between the pyrazinyl and 2(1H)-pyrazylidene forms of pyrazineacetonitrile derivatives were studied by IR,1H-NMR and UV spectroscopy. The excess charges and dipole moments for the two tautomers were calculated by the CNDO/2-MO method.

Zusammenfassung

Die Gleichgewichte zwischen Pyrazinyl- und 2(1H)-Pyrazyliden-Formen von Pyrazinacetonitril-Derivaten wurden mittels IR-, PMR- und UV-Spektroskopie untersucht. Die Überschußladungen und Dipolmomente der zwei Tautomeren wurden nach dem CNDO/2-MO-Verfahren berechnet.

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References

  1. Pomore N. D., J. Med. Chem.11, 431 (1968).

    Google Scholar 

  2. Schwartz N.,Mohrbacher R. J., USA-Patent 3.901.855 (1975).

  3. Pilarski B.,Foks H., Polish-Patent P-232409 (1981).

  4. Pilarski B.,Foks H., Polish-Patent P-234716 (1982).

  5. Junek H., Monatsh. Chem.96, 2046 (1965).

    Google Scholar 

  6. Junek H., Monatsh. Chem.95, 1201 (1964).

    Google Scholar 

  7. Junek H., Monatsh. Chem.95, 1473 (1964).

    Google Scholar 

  8. Gutsche C. D., Voges H. W., J. Org. Chem.32, 2685 (1967).

    Google Scholar 

  9. Ishiguro Y., Funakoshi K., Saeki S., Hamana M., Heterocycles14, 179 (1980).

    Google Scholar 

  10. Borror A. L., Haeberer A. F., J. Org. Chem.30, 243 (1965).

    Google Scholar 

  11. Lapatshev W. W., Zaguliaieva O. A., Mamaiev W. P., Khim. Geterotsikl. Soedin.11, 1544 (1978).

    Google Scholar 

  12. Lapatshev W. W., Zaguliaieva O. A., Mamiev W. P., Khim. Geterotsikl. Soedin.3, 395 (1977).

    Google Scholar 

  13. Siedova W. F., Mamaiev W. P., Khim. Geterotsikl. Soedin.6, 827 (1979).

    Google Scholar 

  14. Hayashi E., Miyagishima T., Yakugaku Zasshi87, 1103 (1967).

    Google Scholar 

  15. Mondelli R., Merlini L., Tetrahedron22, 3253 (1966).

    Google Scholar 

  16. Chakrabartty S. K., Levine R., J. Heterocycl. Chem.4, 109 (1967).

    Google Scholar 

  17. Pople J. A., Segal G. A., J. Chem. Phys.44, 3289 (1966).

    Google Scholar 

  18. Dobosh P. A., QCPE11, 141 (1969).

    Google Scholar 

  19. Wheatley P., Acta Cryst.10, 182 (1957).

    Google Scholar 

  20. Loew G.,Burt S.,Nomura P.,Macleny R., ACS Symp. Series No. 112, Computer-Assisted Drug Design (Olson C.,Christoffersen R. E., eds.). Amer. Chem. Soc. 1979.

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Authors and Affiliations

  1. Faculty of Pharmacy, Medical Academy, PL-80-416, Gdańsk, Poland

    Bogusław Pilarski, Henryk Foks, Krzysztof Osmiałowski & Roman Kaliszan

Authors
  1. Bogusław Pilarski
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  2. Henryk Foks
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  3. Krzysztof Osmiałowski
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  4. Roman Kaliszan
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Pilarski, B., Foks, H., Osmiałowski, K. et al. Studies on pyrazinyl-pyrazylidene tautomerism of pyrazine-acetonitrile derivatives. Monatsh Chem 115, 179–185 (1984). https://doi.org/10.1007/BF00798408

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  • DOI: https://doi.org/10.1007/BF00798408

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