Conclusion
The studies using adult cardiomyocytes indicate that preconditioning is indeed a genuine phenomenon of the myocardial cell. Our own results show that a pharmacological precontioning protocol can provide a pronounced protective effect-comparable to the extent of protection in whole myocardium. The isolation procedure does, therefore, nor render cardio-myocytes unable to exhibit a clear preconditioning effect.
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Piper, H.M., Ladilov, Y.V. Ischemic preconditioning on the cellular level. Basic Res Cardiol 92 (Suppl 2), 32–33 (1997). https://doi.org/10.1007/BF00797203
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DOI: https://doi.org/10.1007/BF00797203