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The Phenomenon of Remote Preconditioning of the Heart and Its Main Manifestations

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Remote ischemic preconditioning prevents reperfusion apoptosis of cardiomyocytes and has infarct-limiting effects which persist in experiments on isolated perfused hearts. Remote preconditioning promotes recovery of cardiac contractility during reperfusion but has no effect on the frequency of occlusional and reperfusional ventricular arrhythmias. Remote preconditioning has a moderate anti-inflammatory effect. This article provides a review and the conclusions are based on published data.

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Authors and Affiliations

  1. Research Institute of Cardiology, Tomsk, Russia

    L. N. Maslov, Yu. K. Podoksenov, S. Yu. Tsibul’nikov & A. S. Gorbunov

  2. Research Institute of Complex Problems in Cardiovascular Diseases, Kemerovo, Russia

    A. V. Tsepokina, M. V. Khutornaya & A. G. Kutikhin

  3. Department of Physiology, Hebei Medical University, Shiojiazhuang, China

    Y. Zhang

  4. Department of Physiology, Fourth Military Medical University, Xian, Shaanxi Province, China

    J.-M. Pei

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  1. L. N. Maslov
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Correspondence to L. N. Maslov.

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Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 102, No. 4, pp. 398–410, April, 2016.

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Maslov, L.N., Podoksenov, Y.K., Tsibul’nikov, S.Y. et al. The Phenomenon of Remote Preconditioning of the Heart and Its Main Manifestations . Neurosci Behav Physi 47, 667–674 (2017). https://doi.org/10.1007/s11055-017-0453-8

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