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Changes in monoamine concentration and monoamine oxidase activity in the arcuate nucleus of the hypothalamus during the estrous cycle

  • Experimental Biology
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Abstract

The concentration of monoamines (MA) and activity of monoamine oxidase (MAO) in the neurons of the hypothalamic arcurate nucleus were investigated during the estrous cycle. The MA concentration was increased in estrus and reduced in diestrus. MAO activity, on the other hand, was highest in metestrus-diestrus and fell sharply in estrus; definite negative correlation was thus observed between these parameters. The overall change in the MA concentration as well as the change in MAO activity in the arcuate nucleus were shown to be brought about by only a relatively small proportion of its cells, about the same in both cases (15–20% of their total number).

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Authors
  1. V. A. Grantyn
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  2. G. V. Ivanova
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Grantyn, V.A., Ivanova, G.V. Changes in monoamine concentration and monoamine oxidase activity in the arcuate nucleus of the hypothalamus during the estrous cycle. Bull Exp Biol Med 78, 1066–1068 (1974). https://doi.org/10.1007/BF00796670

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  • DOI: https://doi.org/10.1007/BF00796670

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