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Changes in subcutaneous connective tissue of rats after injection of cortisone

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The author studied the effect of cortisone on the relative quantities of different cell forms on the histochemical characterstics of cells and of ground substance in the subcutaneous tissue of normal rats. Cortisone stimulated the process of fibroblast differentiation, causing a striking increase in the mean percentage of the most differentiated fibroblasts (fibrocytes). Cortisone provoked no degeneration of fibroblasts or any changes of histochemical peculiarities in the ground substance or in the connective tissue cells. No increase in the amount of the ground substance was noted during differentiation of fibroblasts into fibrocytes.

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Literature Cited

  1. I. A. Alov, Doklady Akad. Nauk. SSSR118, 584 (1958)

    Google Scholar 

  2. J. M. Vasiliev, Doklady Akad. Nauk. SSSR114, 414 (1957).

    Google Scholar 

  3. U. M. Vasiliev, Vopr. onkol.4, 11 (1958).

    Google Scholar 

  4. V. G. Eliseev, Arkh. Anat. Gistol. i Embriol.18, 51 (1938).

    Google Scholar 

  5. N. V. Popova, Izvestiya Akad. Nauk. SSSR Ser. Biol. No. 1, 75(1955).

    Google Scholar 

  6. V. V. Shikhodyrov, Arkh. Patol. No. 12, 56(1958).

    Google Scholar 

  7. F. Allison, M. Smith, and B. Wood, J. Exp. Med.102, 669(1955).

    Google Scholar 

  8. G. Asboe-Hansen, Acta Endocrinol.9, 29(1952).

    Google Scholar 

  9. G. Asboe-Hansen, Proc. Soc. Exp. Biol. Med.80, 677(1952).

    Google Scholar 

  10. G. Asboe-Hansen, Cancer Res.14, 94(1954).

    Google Scholar 

  11. J. Blunt, et al., Proc. Soc. Exp. Biol. Med.73, 678(1950).

    Google Scholar 

  12. C. Cavallero and C. Braccini, Proc. Soc. Exp. Biol. Med.78, 141(1951).

    Google Scholar 

  13. T. Dougherty and G. Schneebeli, Proc. Soc. Exp. Biol. Med.75, 854(1950).

    Google Scholar 

  14. R. Ebert and W. Barclay, Ann. Intern. Med.37 (1952).

  15. C. Whorton, Proc. Soc. Exp. Biol. Med.76, 754(1951).

    Google Scholar 

  16. E. Kuionen, Acta Phys. Scand.24(1951).

  17. L. Layton, Proc. Soc. Exp. Biol. Med.76, 596(1951).

    Google Scholar 

  18. V. Menkin, Rev. Canad. Biol.12, 239(1953).

    Google Scholar 

  19. C. Ragan, et al., Proc. Soc. Exp. Biol. Med.72, 718(1949).

    Google Scholar 

  20. R. Shapiro, B. Taylor, and M. Taubenhaus Proc. Soc. Exp. Biol. Med.76, 854(1951).

    Google Scholar 

  21. M. Taubenhaus and G. Amromin, J. Lab. Clin. Med.36, 7(1950).

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Tumor Culture Institute Experimental and Clinical Oncology, AMN SSSR, Moscow

    Yu. A. Rovenskii

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  1. Yu. A. Rovenskii
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Rovenskii, Y.A. Changes in subcutaneous connective tissue of rats after injection of cortisone. Bull Exp Biol Med 50, 735–737 (1961). https://doi.org/10.1007/BF00796051

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  • DOI: https://doi.org/10.1007/BF00796051

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