A study of higher nervous activity in experimental tuberculosis

Summary

The author studied conditioned secretory reflexes in dogs in experimental tuberculosis prior to treatment and during streptomycin therapy. As established, tuberculosis provokes considerable disturbances of the brain function, manifested in depression of the positive conditioned salivary reflexes and in intensification of the process of sequential inhibition. The disturbance of differentiation was less regular in character. It was possible to reverse the functional changes occurring in the ceretonal cortex by streptomycin therapy. However, normalization of the indices of the conditioned reflex salivary secretion took place later than normalization of the clinical indices in the sick animals.