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The effect of vitamin B12 on the reverse development of cholesterol atherosc lerosis in rabbits

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Prolonged vitamin B12 administration promotes reverse development of atheromatous elements in the rabbit aorta, affected by cholesterol atherosclerosis. Evidently, accelerated reverse development of choloesterol atherosclerosis is connected with the action of vitamin B12 upon the concentration of the lipids in the blood serum.

One cannot exclude, however, the direct activating effect of the vitamin upon the vascular wall elements on which depends the resorption and removal of lipids infiltrating its intima.

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Authors and Affiliations

  1. Institute of Therapy of the AMN SSSR, Moscow

    L. N. Ignatova

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  1. L. N. Ignatova
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Ignatova, L.N. The effect of vitamin B12 on the reverse development of cholesterol atherosc lerosis in rabbits. Bull Exp Biol Med 50, 686–689 (1961). https://doi.org/10.1007/BF00796036

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  • DOI: https://doi.org/10.1007/BF00796036

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