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Combined effect of hydrocortisone and some water-soluble vitamins on the barrier function of the inflammatory focus

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The object of study was the influence of various separately taken doses of hydrocortisone and vitamins C, B1, B2, B6, B12, and Bc, and of paired combinations of hydrocortisone with each of the vitamins on the barrier properties of a focus of turpentine inflammation. It has been found that in case of a paired combination of small doses of hydrocortisone with vitamins C, B1, and B6 there is potentiation of the anti-inflammatory effect. Combination of large doses of cortisone and vitamins gives rise to antagonistic relationships.

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Literature Cited

  1. I. I. Islamov and G. L. Mednik, Trudy Dushanbinsk, Med. Inst., Vol. 21, No. 3 (1956), p. 257.

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Authors and Affiliations

  1. Department of Pharmacology, Perm' Medical Institute, Moscow

    Yu. S. Grosman & E. M. Koz'minykh

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  1. Yu. S. Grosman
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  2. E. M. Koz'minykh
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Grosman, Y.S., Koz'minykh, E.M. Combined effect of hydrocortisone and some water-soluble vitamins on the barrier function of the inflammatory focus. Bull Exp Biol Med 62, 1121–1123 (1966). https://doi.org/10.1007/BF00795454

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  • DOI: https://doi.org/10.1007/BF00795454

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