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Comparative biochemical and histochemical study of the lipids of the liver and heart in experimental hypervitaminosis B1 in pigeons

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Administration of 100 times the physiological doses of thiamine to pigeons for 20–30 days caused considerable shifts in the lipid metabolism. The total lipid content increases in the liver; microscopically this is manifested in the form of intensified intracellular deposition of fat granules. The phospholipid content in the heart rises with a tendency for accumulation of total lipids. Because of the uneven fat distribution in this organ a comparative microscopic examination gave no definite results. The cholesterol content of the heart and liver did not differ in experimental and control birds.

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Ostrovskii, Y.M., Nikitin, V.S. Comparative biochemical and histochemical study of the lipids of the liver and heart in experimental hypervitaminosis B1 in pigeons. Bull Exp Biol Med 56, 1081–1082 (1963). https://doi.org/10.1007/BF00792979

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  • DOI: https://doi.org/10.1007/BF00792979

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