Summary
Administration of 100 times the physiological doses of thiamine to pigeons for 20–30 days caused considerable shifts in the lipid metabolism. The total lipid content increases in the liver; microscopically this is manifested in the form of intensified intracellular deposition of fat granules. The phospholipid content in the heart rises with a tendency for accumulation of total lipids. Because of the uneven fat distribution in this organ a comparative microscopic examination gave no definite results. The cholesterol content of the heart and liver did not differ in experimental and control birds.
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Literature Cited
I. A. Myasnikova, Transactions of the Naval Medical Academy [in Russian], Vol. 8, p. 140. Leningrad (1947).
Yu. M. Ostrovskii, Ukr. biokhim. zh., 4, 617 (1959).
Yu. M. Ostrovskii, Byull. éksper. biol., 7, 62 (1961).
Yu. M. Ostrovskii, in book: Abstracts of Sectional Proceedings of the 5th International Biochemical Congress [in Russian], Vol. 2, p. 186. Moscow (1961).
J. Eys, Fed. Proc., Vol. 19, No. 1, Pt. 1, p. 26 (1960).
D. S. Goodman, in book: Fifth International Biochemical Congress. Biosynthesis of Lipids (Symposium 7) [in Russian], Book 8, p. 19. Moscow (1961).
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Ostrovskii, Y.M., Nikitin, V.S. Comparative biochemical and histochemical study of the lipids of the liver and heart in experimental hypervitaminosis B1 in pigeons. Bull Exp Biol Med 56, 1081–1082 (1963). https://doi.org/10.1007/BF00792979
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DOI: https://doi.org/10.1007/BF00792979