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The reflex effect of certain drugs acting on the receptors of the mesenteric veins in the cat

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

By employing the perfusion method of the humorally isolated protion of the anterior mesenteric vein in cat the author studied the reflex effect of solutions of adrenalin (1∶106), caffeine sodium benzoate (1∶103), strophanthin(1∶2·106), glyceryl trinitrate (1∶2·105) and cardiazol (1∶2·106) on the heart rate, arterial pressure, and respiration. Adrenalin provoked a rise of arterial pressure and stimulation of respiration by reflex action, while other substances mostly reduced the arterial pressure and depressed the respiration. Caffeine frequently decreased the rate heart. The reflex origin of these reactions was proved by control experiments with 2% procaine solution and labeled phosphorus P32.

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Authors and Affiliations

  1. Department of Physiology of the Khabarovsk Medical Institute, Khabarovsk, USSR

    N. F. Konovalov

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  1. N. F. Konovalov
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Konovalov, N.F. The reflex effect of certain drugs acting on the receptors of the mesenteric veins in the cat. Bull Exp Biol Med 48, 1509–1512 (1959). https://doi.org/10.1007/BF00792746

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  • DOI: https://doi.org/10.1007/BF00792746

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